Josef Köhrle Selected Research

Thyroid Neoplasms (Thyroid Cancer)

11/2015	Biosynthesis of 3-Iodothyronamine From T4 in Murine Intestinal Tissue.
10/2015	Selenium and the thyroid.
6/2011	Evidence for extrathyroidal formation of 3-iodothyronamine in humans as provided by a novel monoclonal antibody-based chemiluminescent serum immunoassay.
8/2010	Proteomic approach reveals novel targets for retinoic acid-mediated therapy of thyroid carcinoma.
3/2009	Retinoic acid-mediated down-regulation of ENO1/MBP-1 gene products caused decreased invasiveness of the follicular thyroid carcinoma cell lines.
10/2007	Selenoproteins of the thyroid gland: expression, localization and possible function of glutathione peroxidase 3.
6/2005	Free-flow isoelectric focusing of proteins remaining in cell fragments following sonication of thyroid carcinoma cells.
10/2004	Guard your master: thyroid hormone receptors protect their gland of origin from thyroid cancer.
10/2004	CD82, and CD63 in thyroid cancer.
6/2004	Real time RT-PCR analysis of thyroglobulin mRNA in peripheral blood in patients with congenital athyreosis and with differentiated thyroid carcinoma after stimulation with recombinant human thyrotropin.

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Josef Köhrle Research Topics

Disease

17	Neoplasms (Cancer) 01/2024 - 08/2002
15	Hyperthyroidism 05/2024 - 12/2013
14	Body Weight (Weight, Body) 01/2022 - 06/2007
12	Thyroid Neoplasms (Thyroid Cancer) 11/2015 - 08/2002
9	Hypothyroidism 06/2022 - 10/2002
7	Thyroid Diseases (Thyroid Disease) 02/2023 - 10/2013
6	Goiter 10/2015 - 08/2002
6	Carcinoma (Carcinomatosis) 05/2005 - 08/2002
5	Obesity 06/2022 - 01/2015
5	Sepsis (Septicemia) 01/2019 - 01/2008
5	Allan-Herndon-Dudley syndrome 07/2016 - 09/2010
4	Seizures (Absence Seizure) 11/2022 - 07/2004
4	Critical Illness (Critically Ill) 12/2016 - 04/2002
4	Graves Disease (Basedow Disease) 10/2015 - 02/2013
3	Ataxia (Dyssynergia) 11/2022 - 02/2008
3	Thyrotoxicosis 01/2020 - 10/2016
3	Type 2 Diabetes Mellitus (MODY) 01/2018 - 07/2013
3	Hepatocellular Carcinoma (Hepatoma) 01/2017 - 11/2012
3	Inflammation (Inflammations) 09/2015 - 05/2010
3	Follicular Adenocarcinoma 08/2010 - 04/2004
3	Carcinogenesis 09/2009 - 01/2003
2	Hyperplasia 01/2023 - 12/2020
2	Non-alcoholic Fatty Liver Disease 06/2022 - 01/2021
2	Insulin Resistance 12/2019 - 09/2015
2	Cachexia 01/2019 - 11/2012
2	Atrial Fibrillation 01/2019 - 06/2015
2	Cardiovascular Diseases (Cardiovascular Disease) 10/2016 - 09/2014
2	Atherosclerosis 10/2016 - 10/2014
2	Hyperlipidemias (Hyperlipidemia) 10/2016 - 01/2015
2	Autoimmune Thyroiditis (Lymphomatous Thyroiditis) 10/2015 - 10/2013
2	Hashimoto Disease (Thyroiditis, Hashimoto) 10/2015 - 11/2014
2	Graves Ophthalmopathy 11/2014 - 02/2013
2	Fibrosis (Cirrhosis) 02/2012 - 10/2011
2	Thyroid Nodule (Nodule, Thyroid) 04/2011 - 12/2006
2	Intellectual Disability (Idiocy) 03/2011 - 12/2009
2	Adenoma (Adenomas) 08/2010 - 01/2003
2	Congenital Hypothyroidism (Cretinism) 12/2009 - 10/2002
2	Anaplastic Thyroid Carcinoma 04/2004 - 08/2002
2	Colonic Neoplasms (Colon Cancer) 01/2004 - 01/2003
1	Osteoporosis 05/2024
1	Gastrointestinal Diseases (Functional Gastrointestinal Disorders) 01/2024
1	Dystonia (Limb Dystonia) 11/2022
1	Periventricular Nodular Heterotopia 08/2021
1	Hypertrophy 12/2020
1	Weight Loss (Weight Reduction) 01/2019
1	Heart Failure 01/2019
1	Hyperglycemia 01/2018
1	Uveal melanoma 01/2018
1	Melanoma (Melanoma, Malignant) 01/2018
1	Pre-Eclampsia (Preeclampsia) 01/2018

Drug/Important Bio-Agent (IBA)

25	Thyroid HormonesIBA 02/2023 - 10/2002
18	SeleniumIBA 11/2022 - 09/2002
11	Thyroxine (Levothyroxine)FDA LinkGeneric 05/2022 - 04/2002
11	Iodide Peroxidase (Deiodinase)IBA 01/2022 - 04/2002
11	Messenger RNA (mRNA)IBA 01/2018 - 06/2003
10	Selenoprotein PIBA 01/2024 - 09/2002
9	3,5-diiodothyronineIBA 01/2021 - 09/2014
8	Triiodothyronine (Liothyronine)FDA LinkGeneric 05/2022 - 04/2002
7	Biomarkers (Surrogate Marker)IBA 01/2020 - 06/2004
7	Proteins (Proteins, Gene)FDA Link 01/2020 - 09/2002
6	Selenoproteins (Selenoprotein)IBA 03/2010 - 01/2004
5	Hormones (Hormone)IBA 01/2021 - 07/2010
5	3-iodothyronamineIBA 01/2019 - 01/2015
5	IodineIBA 09/2015 - 10/2002
4	Trace Elements (Biometals)IBA 10/2013 - 01/2004
4	EnzymesIBA 08/2010 - 04/2002
4	Glutathione PeroxidaseIBA 08/2005 - 01/2003
3	AntibodiesIBA 11/2017 - 02/2013
3	Thyrotropin (Thyroid-Stimulating Hormone)FDA Link 12/2016 - 06/2004
3	Tretinoin (Retinoic Acid)FDA LinkGeneric 08/2010 - 04/2004
2	Amitrole (Aminotriazole)IBA 01/2022 - 08/2021
2	ProteomeIBA 01/2021 - 01/2017
2	ThyroninesIBA 12/2019 - 01/2017
2	Drinking WaterIBA 11/2017 - 09/2015
2	Oncogene Proteins (Oncogene Protein)IBA 01/2017 - 03/2009
2	Adrenergic Agents (Adrenergic Drugs)IBA 12/2016 - 09/2015
2	Selenium CompoundsIBA 10/2015 - 10/2013
2	Propylthiouracil FDA Link 08/2015 - 12/2013
2	CreatinineIBA 11/2014 - 12/2006
2	ProcalcitoninIBA 05/2011 - 09/2010
2	Reactive Oxygen Species (Oxygen Radicals)IBA 05/2011 - 01/2004
2	RacivirIBA 10/2004 - 08/2002
1	Bone Morphogenetic Protein ReceptorsIBA 05/2024
1	Bone Morphogenetic Proteins (Bone Morphogenetic Protein)IBA 05/2024
1	IodidesIBA 01/2023
1	ParvalbuminsIBA 11/2022
1	LipidsIBA 06/2022
1	MonoiodotyrosineIBA 01/2022
1	PesticidesIBA 08/2021
1	Food Additives (Food Additive)IBA 12/2020
1	Monoclonal AntibodiesIBA 01/2019
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2018
1	C-PeptideIBA 01/2018
1	inhibin AIBA 01/2018
1	Liver GlycogenIBA 01/2018
1	RelaxinIBA 01/2018
1	EndoglinIBA 01/2018
1	IsoflavonesIBA 01/2018

Therapy/Procedure

8	Therapeutics 05/2022 - 04/2004
4	Thyroidectomy 01/2019 - 06/2004